Effects of Clofibrate and Sulfinpyrazone
نویسنده
چکیده
Platelet survival time was measured (autologous labelling with 51chromium) in 68 men with coronary artery disease (CAD). Survival was shortened slightly (3.2 ± 0.04 days; mean ± SEM) as compared to normal (3.7 ± 0.04 days; N = 18; P < 0.001), and 60% had shortened survival (< 3.3 days). Thirty-seven had hyperlipoproteinemia (36 with Type IV and one with Type III) and platelet survival was shortened (3.1 ± 0.10 days) and significantly different from survival of men with normal lipoproteins (3.3 ± 0.12 days; P < 0.05). Twenty-two with shortened platelet survival and CAD received either clofibrate or sulfin-
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